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Epilepsy: Cannabidiol in Patients With Treatment-Resistant Epilepsy

Epilepsy: Cannabidiol in Patients With Treatment-Resistant Epilepsy

KEY TAKEAWAYS:

  • CBD oil treatment showed a favorable safety and adverse event profile
  • There was a 36.5% reduction in motor seizures frequency over the treatment period and a reduction of 35.5% in seizures of all types
  • For motor seizures, 39% of patients had a reduction of 50% or more, 21% of 70% or more and 9% had a reduction of 90% or more
  • For all seizure types, 37% of patients had a reduction of 50% or more, 22% of 70% or more, and 8% had a reduction of 90% or more
  • Most patients who achieved seizure freedom or a reduction of 90% had never experienced a previous antiepileptic drug regimen that was as efficacious as CBD oil

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Arthritis: Topical CBD use Reduces Inflammation and Pain-Related Behaviours Linked to Arthritis

Arthritis: Topical CBD use Reduces Inflammation and Pain-Related Behaviours Linked to Arthritis

KEY TAKEAWAYS:

  • Topical CBD proved to be an effective symptomatic, anti-inflammatory and anti-hyperalgesic treatment in arthritis
  • The subjects didn’t suffer any alteration in their activity levels or motor abilities.
  • A dose of 6.2mg/day of CBD significantly reduced swelling and synovial thickness
  • Transdermal CBD use improved pain, reducing the median score from 4 to 1.5 (0-5 scale)
  • Only after 2 days of CBD treatment, there was a significant improvement of heat hypersensitivity, which persisted throughout the experiment
  • Pro-inflammatory activity dropped as low as non-pathological levels after using CBD

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Candid CBD study on Anxiety and Stress

Anxiety: Cannabidiol Blocks Long-Lasting Behavioral Consequences of Predator Threat Stress

KEY TAKEAWAYS:

  • CBD can prevent the long-lasting anxiogenic effect promoted by traumatic events
  • When compared to the control group, the reduction in anxiety behavior was greater with CBD than with the common antidepressant used in PTSD treatment
  • CBD anti-stress effects could depend on serotonin (5HT1A) receptor activation; serotonin contributes to the feeling of well-being, reason why it’s often labeled happiness hormone
  • The study suggest CBD has beneficial potential for the treatment of PTSD

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