Candid Summaries on CBD Studies

KEY TAKEAWAYS:

• Previous findings report CBD’s ability to inhibit tumor invasion and cancer metastasis
• 50% of dogs over 10 years of age have cancer and 20% of cats will develop cancer in their lifetime
  
• Superior tumor cell killing was achieved with CBD than with 4 Gy (unit of radiation dose) of RT alone
• Results support a greater effectiveness in killing tumor cells when combining CBD and radiotherapy (RT)
• CBD use in combination with RT increased the survival rates of the studied mice
• There is a clear demonstration of a bigger survival rate of CBD-treated mice comparing with the control group (no treatment)
• In situ (in the exact local) delivery of CBD with smart biomaterials allows bigger concentrations of CBD to reach its target
• CBD treatment occasioned an 80% survival rate (vs 50% in the control group) in mice with tumors, whereas the use of smart biomaterials loaded with CBD resulted in a 100% survival rates 

KEY TAKEAWAYS:

• Long-term use of cannabinoids was well tolerated and no loss of effect was perceived
• Patients on treatment did not seek to increase cannabinoids dose nor did they seek any other treatment for pain relief
• Quality of life domains of insomnia, fatigue and pain showed an improvement after cannabinoid administration and no harmful effect was observed in the domain of cognitive functioning

KEY TAKEAWAYS:

• 43% of participants experienced a  ≥30% reduction in cancer-related pain intensity after cannabinoid treatment 
• 20% of cats and 25% of dogs will be diagnosed with cancer in their lifetime
• After 2 weeks of receiving CBD+THC in addition to all other treatments, there was a statistically significant reduction in pain severity when compared with placebo
• The addition of CBD resulted in a increase of 20% in the response rate 
• A greater proportion of patients in the cannabinoid treatment group reduced other pain medication doses whereas the highest proportion of increases in dose was in the placebo group
• Administration of THC+CBD was well tolerated and no safety concerns were identified